NMS-1286937 Catalog No.:M9125-2 Formula: C10H10N2O

Formula: C10H10N2O

3 nM and LRRK2-[G2019S] ~3

The increasing concentrations of BMS-3 result in a strong decrease on the percentage of sperm that undergoes acrosomal exocytosis after stimulation with 20 μM of Progesterone[2]

Exatecan Mesylate (DX-8951f) significantly inhibits the proliferation of several cancer cell lines

cell-permeable γ-secretase inhibitor (IC50= 0

NMS-1286937 Catalog No.:M9125-2 Formula: C10H10N2OOnvansertib, also know as NMS P937, PCM 075 and NMS1286937, is a n orally bioavailable, small molecule Polo like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo like kinase 1 inhibitor NMS 1286937 selectively inhibits PLK1, inducing selective G2 M cell cycle arrest followed by apoptosis in a variety of tumor cells while causing reversible cell cycle arrest at the G1 and G2 stages without apoptosis in normal cells. PLK1