GS-9620 - CAS# 1228585-88-3 iphosphate CAS Number: 459147-39-8

CAS Number: 459147-39-8

CC1ON=C(C=1C1C=CC(=CC=1)S(=O)(=O)NC(=O)CC)C1C=CC=CC=1 |^1:0|

Chemical Name: N-((S)-1-(((S)-2-amino-1-cyclohexyl-2-oxoethyl)amino)-3-cyclohexyl-1-oxopropan-2-yl)isoxazole-5-carboxamide

It also inhibits PLK2 and PLK3 with IC50 of 3

WZ3146 significantly suppresses the growth of EGFR mutation containing cell lines with IC50 of 3 nM in EGFR Del E746_A750 containing HCC827 cells

GS-9620 - CAS# 1228585-88-3 iphosphate CAS Number: 459147-39-8Vesatolimod, also known as GS 9620, is a potent and oral agonist of Toll like receptor 7 developed for finite treatment of chronic hepatitis B viral (HBV) infection, with the goal of inducing a liver targeted antiviral effect without inducing the adverse effects associated with current systemic interferon (IFN ) therapies. GS 9620 demonstrate interferon stimulated gene induction without detectable serum interferon at low oral doses. GS 9620 can induce