BAY 61-3606 - CAS# 732983-37-8 Size:Solid 2 mg CAS Number: 49671-76-3
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BAY 61-3606 - CAS# 732983-37-8 Size:Solid 2 mg CAS Number: 49671-76-3BAY 61 3606 is a potent (Ki = 7. 5 nM) and selective inhibitor of Syk kinase. BAY 61 3606 inhibited not only degranulation (IC50 values between 5 and 46 nM) but also lipid mediator and cytokine synthesis in mast cells. BAY 61 3606 was highly efficacious in basophils obtained from healthy human subjects (IC50 = 10 nM) and seems to be at least as potent in basophils obtained from atopic (high serum IgE) subjects (IC50 = 8. 1 nM). B cell receptor
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