Reversine Size:Solid 10 mg 6(9):e25264
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Reversine Size:Solid 10 mg 6(9):e25264Reversine is a small molecule developed by the group of Peter G. Schultz, used for stem cell dedifferentiation. Reversine is also a novel Aurora kinases inhibitor that inhibits colony formation of human acute myeloid leukemia cells. Reversine inhibits the phosphorylation of histone H3, a direct downstream target of Aurora kinases. Similarly to the Aurora kinase inhibitor VX 680, reversine inhibited colony formation of leukemic cells from patients with
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