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TGR5 Polyclonal Antibody, 100ul Centrifugal Filter and contributes to the regulation

SKU: 99819208787

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TGR5 Polyclonal Antibody, 100ul Centrifugal Filter and contributes to the regulationGPBAR1 encodes a member of the G protein coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.

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Description

and contributes to the regulation of immune responses

The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking

Diseases associated with FAM3D include narcolepsy

E1A-like inhibitor of differentiation-1 (EID-1)

ADAMTS12 (ADAM metallopeptidase with thrombospondin type 1 motif 12) encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family

TGR5 Polyclonal Antibody, 100ul Centrifugal Filter and contributes to the regulationGPBAR1 encodes a member of the G protein coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.

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