MK12 Polyclonal Antibody, 100ul Recombinant Ab Production The gene encodes eIF5B

The gene encodes eIF5B

Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm

Defects in this gene are a cause of hereditary coproporphyria (HCP)

and mutations in DYRK1B were found to cause abdominal obesity-metabolic syndrome 3

The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex

MK12 Polyclonal Antibody, 100ul Recombinant Ab Production The gene encodes eIF5BActivation of members of the mitogen activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress activated protein kinases are one subclass of MAP kinases. The protein encoded by this gene functions as a signal transducer during differentiation of myoblasts to myotubes.