CD264 Polyclonal Antibody, 100ul Liquid Storage Consumables |PTM:S-nitrosylation of Cys-61 affects DNA

|PTM:S-nitrosylation of Cys-61 affects DNA binding

The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest| and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells

The encoded type 2 transmembrane protein may play a role in inflammatory and immune response

Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor

Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex

CD264 Polyclonal Antibody, 100ul Liquid Storage Consumables |PTM:S-nitrosylation of Cys-61 affects DNAThe protein encoded by TNFRSF10D (TNF receptor superfamily member 10d) is a member of the TNF receptor superfamily. This receptor contains an extracellular TRAIL binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL induced cell apoptosis.