ECHA Rabbit Polyclonal Antibody, 20ul Enzyme Activity Assays Diseases associated with MRRF include

Diseases associated with MRRF include epidemic typhus and uremic neuropathy

PIAS1 encodes a member of the protein inhibitor of activated STAT (PIAS) family

Members of the subfamily share similarity in sequence and splice sites

Required for the fusion of plasma membranes and early endosomes

Members of HES6 family regulate cell differentiation in numerous cell types

ECHA Rabbit Polyclonal Antibody, 20ul Enzyme Activity Assays Diseases associated with MRRF includeThis gene encodes the alpha subunit of the mitochondrial trifunctional protein which catalyzes the last three steps of mitochondrial beta oxidation of long chain fatty acids. The mitochondrial membrane bound heterocomplex is composed of four alpha and four beta subunits with the alpha subunit catalyzing the 3 hydroxyacyl CoA dehydrogenase and enoyl CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD