ATF-2 Polyclonal Antibody, 50ul[BT-AP00696] Deep Well Plates Mutations in this gene cause

Mutations in this gene cause Joubert syndrome

An important paralog of this gene is G3BP1

The encoded protein is located in the Xq28 region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and both genes are driven by a CpG-embedded bidirectional promoter

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ATF-2 Polyclonal Antibody, 50ul[BT-AP00696] Deep Well Plates Mutations in this gene causeATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein (activating transcription factor 2) has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c Jun and stimulates CRE dependent transcription. This