HLA-DO Alpha Polyclonal Antibody, 100ul Biomatrix A nonconventional nuclear localization sequence

A nonconventional nuclear localization sequence (NLS) has been found for protein kinase cAMP-dependent type I regulatory subunit alpha which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40)

which shift from the inactive to the active state through the action of RALGDS (MIM 601619)

250mLx4pcs

probably to asymmetric dimethylarginine

There are six pseudogenes of this gene found on chromosomes 2

HLA-DO Alpha Polyclonal Antibody, 100ul Biomatrix A nonconventional nuclear localization sequenceHLA DOA belongs to the HLA class II alpha chain paralogues. HLA DOA forms a heterodimer with HLA DOB. The heterodimer, HLA DO, is found in lysosomes in B cells and regulates HLA DM mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.