PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling The protein (ataxin 2) encoded

The protein (ataxin 2) encoded by ATXN2 has two globular domains near the N-terminus

Several alternatively spliced transcript variants of this gene have been described| but their biological validity has not been determined

It seems to interact in a multiprotein complex with RbAp48 and HDAC3

It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development

This gene encodes a member of the desmocollin protein subfamily

PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling The protein (ataxin 2) encodeddisease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM: