SETBP Rabbit Polyclonal Antibody, 20ul Immunology It has been shown to

It has been shown to play a central role in the physiological regulation of programmed cell death

The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding

Pseudogenes are present on chromosomes 5 and 22

It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus

which is characterized by skeletal dysplasia with generalized limb bone shortening

SETBP Rabbit Polyclonal Antibody, 20ul Immunology It has been shown toThis gene encodes a protein which contains a several motifs including a ski homology region and a SET binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.