Phospho-ACK (Y284) Polyclonal Antibody, 100ul Liquid Handling ＆Storage The protein encoded by CD99

The protein encoded by CD99 is a cell surface glycoprotein involved in leukocyte migration

This cytokine is also found to inhibit endothelial cell proliferation

predominantly in the basket terminal ring area

Mutations in this gene have been associated with congenital insensitivity to pain| anhidrosis| self-mutilating behavior| mental retardation and cancer

This protein is localized in the nucleus and contains an E1A-type zinc finger domain

Phospho-ACK (Y284) Polyclonal Antibody, 100ul Liquid Handling ＆Storage The protein encoded by CD99TNK2 encodes a tyrosine kinase that binds Cdc42Hs in its GTP bound form and inhibits both the intrinsic and GTPase activating protein (GAP) stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C terminal to an SH3 domain. The tyrosine kinase non receptor 2 may be involved in a regulatory mechanism that sustains the GTP bound active form of Cdc42Hs and which is directly linked to a tyrosine