CARD 10 Polyclonal Antibody, 50ul Cell Dissociation This gene encodes a large

This gene encodes a large

Dok-5 protein undergoes tyrosine phosphorylation in response to insulin and insulin-like growth factor-1

Also CD63 has been associated with tumor progression

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Mutations in this gene result in heritable predisposition to colon and stomach cancer

CARD 10 Polyclonal Antibody, 50ul Cell Dissociation This gene encodes a largeThe caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane associated guanylate kinase (MAGUK) family and activates NF kappa B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).