OPG Monoclonal Antibody, 100ul[BT-MCA0960] Gene Synthesis |disease:Defects in EP300 are a

|disease:Defects in EP300 are a cause of Rubinstein-Taybi syndrome (RSTS)

which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily

and come in a convenient re-sealable bag

Only one of the isoforms appears to be a secreted protein

NVL encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily

OPG Monoclonal Antibody, 100ul[BT-MCA0960] Gene Synthesis |disease:Defects in EP300 are aThe protein encoded by this gene is a member of the TNF receptor superfamily. This protein is an osteoblast secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph node organogenesis