MAD1 Polyclonal Antibody, 50ul Antisense Oligonucleotides The encoded protein is a

The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes

Mutations in this gene have been implicated in a neurodevelopmental disorder

and osteogenic sarcoma

Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs

An important paralog of RNF144B is RNF19A

MAD1 Polyclonal Antibody, 50ul Antisense Oligonucleotides The encoded protein is aMAD1L1 (MAD1 mitotic arrest deficient like 1) is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.