YAP Polyclonal Antibody, 20ul[BT-AP09632] sgRNA Library Construction Mutations in COL4A1 cause porencephaly

Mutations in COL4A1 cause porencephaly

Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium

An important paralog of this gene is JMJD7-PLA2G4B

This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells

with the protein encoded by this gene representing the beta subunit

YAP Polyclonal Antibody, 20ul[BT-AP09632] sgRNA Library Construction Mutations in COL4A1 cause porencephalyYAP1 encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.