Integrin Beta2 Polyclonal Antibody, 50ul[BT-AP04586] Diagnostic Probes & Oligos This ubiquitously expressed gene has

This ubiquitously expressed gene has its highest expression in skeletal muscle

Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid

An important paralog of this gene is MPV17L2

is exclusively expressed in testis but it has also been found in a wide variety of cancer tissues and cell lines

This cytokine is found to be preferentially expressed in monocytes

Integrin Beta2 Polyclonal Antibody, 50ul[BT-AP04586] Diagnostic Probes & Oligos This ubiquitously expressed gene hasITGB2 encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell surface proteins that participate in cell adhesion as well as cell surface mediated signalling. The integrin subunit beta 2 plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.