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MLK1/2 Polyclonal Antibody, 100ul Insect Expression In mouse| deletion of this

SKU: 77241633512

4.4
PLN123.75 PLN172.75

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MLK1/2 Polyclonal Antibody, 100ul Insect Expression In mouse| deletion of thisThe protein encoded by MAP3K10 is a member of the serine threonine kinase family. This kinase has been shown to activate MAPK8 JNK and MKK4 SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

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Description

In mouse| deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium

50)| which catalyzes the rate-limiting step of the de novo synthesis of sphingolipids (Hornemann et al

Gene Ontology (GO) annotations related to NPY2R include G-protein coupled receptor activity and calcium channel regulator activity

For example| when activated by SRC| the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi| where it activates Ras

The encoded protein also plays a role in multidrug resistance

MLK1/2 Polyclonal Antibody, 100ul Insect Expression In mouse| deletion of thisThe protein encoded by MAP3K10 is a member of the serine threonine kinase family. This kinase has been shown to activate MAPK8 JNK and MKK4 SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

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