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DGCR8 Rabbit Polyclonal Antibody, 100ul Adeno-associated Virus Packaging This gene is situated next

SKU: 77215223241

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DGCR8 Rabbit Polyclonal Antibody, 100ul Adeno-associated Virus Packaging This gene is situated nextThis gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double stranded RNA binding protein that functions as the non catalytic subunit of the microprocessor complex. This protein is required for binding the double stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein Drosha. Alternate splicing results in

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Description

This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5)

Inhibition of the encoded protein can lead to apoptosis

The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al

Tumor necrosis factor receptor superfamily member 1B and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins

Among its related pathways are Activation of cAMP-Dependent PKA and Neuropathic Pain-Signaling in Dorsal Horn Neurons

DGCR8 Rabbit Polyclonal Antibody, 100ul Adeno-associated Virus Packaging This gene is situated nextThis gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double stranded RNA binding protein that functions as the non catalytic subunit of the microprocessor complex. This protein is required for binding the double stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein Drosha. Alternate splicing results in

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