Rac GAP1 Polyclonal Antibody, 100ul[BT-AP07592] Transporters The protein encoded by this

The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters

Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11)

and progressive pulmonary fibrosis

as well as in cell-cell and cell-matrix adhesion signaling

This enzyme can act as a sphingolipid delta(4)-desaturase| and also as a sphingolipid C4-hydroxylase

Rac GAP1 Polyclonal Antibody, 100ul[BT-AP07592] Transporters The protein encoded by thisRACGAP1 encodes a GTPase activating protein (GAP) that is a compoment of the centralspindlin complex. Rac GTPase activating protein 1 binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho mediated signals. Rac GTPase activating protein 1 plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for RACGAP1. There is a