ULA1 Polyclonal Antibody, 100ul General Lab Use Several alternatively spliced transcript variants

Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported

Mutations in this gene have been associated with Win

PTM:Dually phosphorylated on Thr-291 and Tyr-293

It contains heparin-

are found to form a gene cluster on chromosome 3p

ULA1 Polyclonal Antibody, 100ul General Lab Use Several alternatively spliced transcript variantsThe protein encoded by this gene binds to the beta amyloid precursor protein. Beta amyloid precursor protein is a cell surface protein with signal transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin like protein. This protein is required for cell cycle progression through the S M checkpoint. Three