GNA11 Polyclonal Antibody, 50ul Thermo Mix ANO2 belongs to a family

ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al

This gene encodes a type II membrane protein that belongs to the ITM2 family

Mediates the uptake of pyruvate into mitochondria

Luciferase catalyzes a bioluminescent reaction which requires the substrate luciferin as well as Mg2+ and ATP

which upon ligand binding exhibits greatly increased guanylyl cyclase activity

GNA11 Polyclonal Antibody, 50ul Thermo Mix ANO2 belongs to a familyThe protein encoded by this gene belongs to the family of guanine nucleotide binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha 11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2).