CCBE1 Polyclonal Antibody, 50ul Biochemical Reagents During abscission

During abscission

Alternative splicing of TAF1 results in multiple transcript variants

act as an integration point for multiple biochemical signals

The activated form of eukaryotic translation initiation factor 2 alpha kinase 2 can phosphorylate translation initiation factor EIF2S1

but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues

CCBE1 Polyclonal Antibody, 50ul Biochemical Reagents During abscissionThis gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia lymphedema syndrome, a generalized lymphatic dysplasia in humans.