ADI1 Polyclonal Antibody, 100ul Plates & Dishes Protein-glutamine gamma-glutamyltransferase 2 encoded by

Protein-glutamine gamma-glutamyltransferase 2 encoded by TGM2 acts as a monomer

The encoded protein acts as a transcription factor and may be autoregulatory

The protein has broad-spectrum antimicrobial activity against bacteria and fungi

Sumoylation requires heterodimerization with JUN and is enhanced by mitogen stimulation

2004 [PubMed 15153109])

ADI1 Polyclonal Antibody, 100ul Plates & Dishes Protein-glutamine gamma-glutamyltransferase 2 encoded byThis gene encodes an enzyme that belongs to the aci reductone dioxygenase family of metal binding enzymes which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. Alternative splicing results in multiple transcript variants encoding different isoforms.