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CD209 Polyclonal Antibody, 100ul DNA Oligo Synthesis The composition of the APC

SKU: 6803402099

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SEK141.00 SEK176.00

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CD209 Polyclonal Antibody, 100ul DNA Oligo Synthesis The composition of the APCCD209 encodes a transmembrane receptor and is often referred to as DC SIGN because of its expression on the surface of dendritic cells and macrophages. The CD209 molecule is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N terminal transmembrane domain, a tandem repeat neck

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Description

The composition of the APC is highly conserved in organisms from yeast to humans

Disruption of this gene by translocation has been associated with haplo-insufficiency and renal cell carcinomas

It has also been implicated in the pathogenesis of small cell lung cancer

Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS)

Acts as a regulator of PCK1 expression and gluconeogenesis by a mechanism that involves

CD209 Polyclonal Antibody, 100ul DNA Oligo Synthesis The composition of the APCCD209 encodes a transmembrane receptor and is often referred to as DC SIGN because of its expression on the surface of dendritic cells and macrophages. The CD209 molecule is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses with a large impact on public health. The protein is organized into three distinct domains: an N terminal transmembrane domain, a tandem repeat neck

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