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SMG9 Polyclonal Antibody, 100ul Isothermal Amplification Although its function is unknown|

SKU: 66445950271

4.7
USD141.00 USD174.00

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SMG9 Polyclonal Antibody, 100ul Isothermal Amplification Although its function is unknown|This gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features.

Store: humanprojects.de · Domain: humanprojects.de

Description

Although its function is unknown| the observation that this gene is conserved in the mouse implies it has some function

Acts as a nucleolar anchoring protein for DDX47

Contains 1 Ras-associating domain

Y-box-binding protein 2 binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes

Interacts with AKAP13

SMG9 Polyclonal Antibody, 100ul Isothermal Amplification Although its function is unknown|This gene encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in this gene cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features.

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