PKHA1 Polyclonal Antibody, 100ul Tubes The protein may modulate lysosomal

The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors

2| has been defined by analysis of patients with partial trisomy 21

It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum

or a potent one when fused with a heterologous protein containing a KRAB B-domain

which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell

PKHA1 Polyclonal Antibody, 100ul Tubes The protein may modulate lysosomalThis gene encodes a pleckstrin homology domain containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4 bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this