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CD47 Polyclonal Antibody, 100ul Cell Senescence Alternative splicing of downstream exons

SKU: 65595044358

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CD47 Polyclonal Antibody, 100ul Cell Senescence Alternative splicing of downstream exonsCD47 encodes a CD47 molecule, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript

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Description

Alternative splicing of downstream exons is also observed| which results in different forms of the stimulatory G-protein alpha subunit| a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses

The encoded protein may also play a role in specialized leukocyte functions such as immunological response and bactericidal activity

TNFAIP8 (TNF Alpha Induced Protein 8) is a Protein Coding gene

Interacts with HEXIM1 and MAP1S

The central feature of this gene family is a novel

CD47 Polyclonal Antibody, 100ul Cell Senescence Alternative splicing of downstream exonsCD47 encodes a CD47 molecule, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes. Alternatively spliced transcript

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