Smad3 Monoclonal Antibody(8B5), 50ul Cell Function Analysis Mutations in this gene result

Mutations in this gene result in dominant late-onset Fuchs corneal dystrophy

Defects in RB1 are a cause of childhood cancer retinoblastoma (RB)

This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere

which are stem-loop structures found in the 5' UTR of ferritin mRNA

The corticotropin releasing hormone receptor 2 encoded by CRHR2 belongs to the G-protein coupled receptor 2 family

Smad3 Monoclonal Antibody(8B5), 50ul Cell Function Analysis Mutations in this gene resultThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of