CD63 Polyclonal Antibody, 50ul[BT-AP02478] Molecular Sciences Mutations in ACTA1 cause nemaline

Mutations in ACTA1 cause nemaline myopathy type 3

member RAS oncogene family encoded by RAB40B has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles

TBX3 (T-box 3) is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain

Interacts with HDAC3

and thus it may function in mitosis

CD63 Polyclonal Antibody, 50ul[BT-AP02478] Molecular Sciences Mutations in ACTA1 cause nemalineKRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. Keratin 8 plays a role in maintaining cellular structural integrity and also functions in signal transduction