Rho A Polyclonal Antibody, 100ul Nucleic Acid Extraction The protein encoded by EDNRB

The protein encoded by EDNRB (endothelin receptor type B) is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system

The expression of this gene may be regulated by peroxisome proliferator-activated receptor gamma

A duplication of LMNB1 is associated with autosomal dominant adult-onset leukodystrophy (ADLD)

and therefore is about 800 aa longer than the other MAGE proteins

GO annotations related to this gene include hydrolase activity and serine-type peptidase activity

Rho A Polyclonal Antibody, 100ul Nucleic Acid Extraction The protein encoded by EDNRBRHOA encodes a member of the Rho family of small GTPases, which cycle between inactive GDP bound and active GTP bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.