NALP4 Rabbit Polyclonal Antibody, 50ul Molecular Biologyn The protein is synthesized as

The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum

Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described

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It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death

This gene encodes a member of the claudin family

NALP4 Rabbit Polyclonal Antibody, 50ul Molecular Biologyn The protein is synthesized asNALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs such as NALP4 have an N terminal pyrin (MEFV; MIM 608107) domain (PYD) followed by a NACHT domain a NACHT associated domain (NAD) and a C terminal leucine rich repeat (LRR) region. The long NALP NALP1 (MIM 606636) also has a C terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs