MC4-R Polyclonal Antibody, 50ul Nucleic Acid Amplification The N-terminal C2 domain associates

The N-terminal C2 domain associates with lipid membranes and mediates its regulation by presenting the active site to its substrate in response to elevations of cytosolic Ca(2+)

The receptor functions as a neurotransmitter-gated ion channel

and interferon (IFN)-gamma

this enzyme has an N-terminal domain with guanine nucleotide exchange (GEF) activity

This gene family contains numerous pseudogenes

MC4-R Polyclonal Antibody, 50ul Nucleic Acid Amplification The N-terminal C2 domain associatesThe protein encoded by MC4R is a membrane bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.