Integrin AlphaL Polyclonal Antibody, 50ul Primary Antibodies Several alpha defensin genes are

Several alpha defensin genes are clustered on chromosome 8

It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells

It binds to integrins of type CD11a / CD18

also known as AARF

secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling

Integrin AlphaL Polyclonal Antibody, 50ul Primary Antibodies Several alpha defensin genes areITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function associated antigen 1 (LFA 1), which is expressed on all leukocytes. LFA 1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1 3