Stat5 Polyclonal Antibody, 100ul[BT-AP08636] Electrophoresis & Labeling This gene is highly expressed

This gene is highly expressed in leukemia cells and may be a good target for therapeutic intervention

This mitochondrial protein initiates the degradation of 1

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This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif

and presented on the cell surface as a heterodimer

Stat5 Polyclonal Antibody, 100ul[BT-AP08636] Electrophoresis & Labeling This gene is highly expressedStat5 is activated in response to a wide variety of ligands including IL 2, GM CSF, growth hormone and prolactin. Phosphorylation at Tyr694 is obligatory for Stat5 activation. This phosphorylation is mediated by Src upon erythropoietin stimulation. Stat5 is constitutively active in some leukemic cell types. Phosphorylated Stat5 is found in some endothelial cells treated with IL 3, which suggests its involvement in angiogenesis and cell motility.