Zic1/2/3/4/5 Polyclonal Antibody, 100ul Electrophoresis & Labeling and pancreatic glucose-stimulated insulin secretion

and pancreatic glucose-stimulated insulin secretion

but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal

beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids

The secretory protein encoded by this gene is produced in gastric surface mucous cells

and it is structurally similar to opioid and somatostatin receptors

Zic1/2/3/4/5 Polyclonal Antibody, 100ul Electrophoresis & Labeling and pancreatic glucose-stimulated insulin secretionZIC1 (Zic family member 1) encodes a member of the ZIC family of C2H2 type zinc finger proteins. Members of this family are important during development. Aberrant expression of ZIC1 is seen in medulloblastoma, a childhood brain tumor. ZIC1 is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. ZIC1 encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.