Phospho-Bim (S59) Polyclonal Antibody, 100ul In vitro Transcription Members of this family can

Members of this family can interact with the elongin B-C adapter complex via their SOCS box domain and further complex with the cullin and ring box proteins to form E3 ubiquitin ligase complexes

The protein encoded by this gene belongs to the SAC domain-containing protein gene family

type 5 (HSAN5)

Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells

The protein contains a putative src homology 2 (SH2) domain

Phospho-Bim (S59) Polyclonal Antibody, 100ul In vitro Transcription Members of this family canBim Bod is a pro apoptotic protein belonging to the BH3 only group of Bcl 2 family members including Bad, Bid, Bik, Hrk, and Noxa that contain a BH3 domain but lack other conserved BH1 or BH2 domains. Bim induces apoptosis by binding to and antagonizing anti apoptotic members of the Bcl 2 family. Interactions have been observed with Bcl 2, Bcl xL, Mcl 1, Bcl w, Bfl 1, and BHRF 1. Bim functions in regulating apoptosis associated with thymocyte negative