Endo G-L1 Polyclonal Antibody, 100ul Molecular Sciences small ubiquitin-like modifier 2 is

small ubiquitin-like modifier 2 is involved in a variety of cellular processes

protecting the lungs against inhaled microorganisms and chemicals

Multiple alternatively spliced transcript variants

The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs

Mutations in this gene have been associated with several diseases

Endo G-L1 Polyclonal Antibody, 100ul Molecular Sciences small ubiquitin-like modifier 2 isEXOG encodes an endo exonuclease with 5' 3' exonuclease activity. The encoded enzyme (endo exonuclease (5' 3'), endonuclease G like) catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.