Ksr2 Polyclonal Antibody, 100ul Cell Proliferation pathway:Lipid metabolism

pathway:Lipid metabolism

Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons

Also expressed in Barrett's esophagus epithelium and in the proximal duodenum

Acts as a GTPase activitor in vitro for CDC42 and RAC1

formerly thought to be a beta chain

Ksr2 Polyclonal Antibody, 100ul Cell Proliferation pathway:Lipid metabolismLocation regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8 mediated signaling. Acts as a negative regulator of MAP3K3 mediated activation of ERK, JNK and NF kappa B pathways, inhibiting MAP3K3 mediated interleukin 8 production.