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Pim-1(Phospho Tyr309) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) and is thought to contribute

SKU: 5268837840

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Pim-1(Phospho Tyr309) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) and is thought to contributeThe protein encoded by this gene belongs to the Ser Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes

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Description

and is thought to contribute to the invasive phennotype of breast cancer and several other tumors

The ectodomain

The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells

RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors

cyclosporin A binds and inactivates the key signaling intermediate calcineurin

Pim-1(Phospho Tyr309) Polyclonal Antibody, 20ul Enzyme-Linked Immunosorbent Assay (ELISA) and is thought to contributeThe protein encoded by this gene belongs to the Ser Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes

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