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Phospho-Bcl-2 (S87) Polyclonal Antibody, 20ul Glassware ARSD is located within a

SKU: 52555304446

4.3
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Phospho-Bcl-2 (S87) Polyclonal Antibody, 20ul Glassware ARSD is located within aBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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Description

ARSD is located within a cluster of similar arylsulfatase genes on chromosome X

proliferation and survival in the adult and the embryo

Alternative splicing of GBA3 results in multiple transcript variants

The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells

Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response

Phospho-Bcl-2 (S87) Polyclonal Antibody, 20ul Glassware ARSD is located within aBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

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