TMEM145 Polyclonal Antibody, 100ul 3D Culture The encoded protein functions in

The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines

These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators

Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer

This gene encodes the largest subunit of RNA polymerase II| the polymerase responsible for synthesizing messenger RNA in eukaryotes

Mutation of this gene results in Brunner syndrome

TMEM145 Polyclonal Antibody, 100ul 3D Culture The encoded protein functions inTMEM145 (transmembrane protein 145) is a 493 amino acid protein encoded by a gene mapping to human chromosome 19. Consisting of around 63 million bases with over 1,400 genes, chromosome 19 makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the