Gab 2 Polyclonal Antibody, 50ul[BT-AP03412] DNA Fragments The encoded protein interacts with

The encoded protein interacts with the cullin-3 protein| a ubiquitin E3 ligase necessary for mitotic cell division

The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus

The expression of this gene can be regulated by insulin

Single nucleotide polymorphisms in this gene may be associated with essential hypertension

encode distinct proteins (PMID: 9207021)

Gab 2 Polyclonal Antibody, 50ul[BT-AP03412] DNA Fragments The encoded protein interacts withGAB2 (GRB2 associated binding protein 2) is a member of the GRB2 associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T and B cell antigen receptors. The protein encoded by GAB2 is the principal activator of