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DTBP1 Rabbit Polyclonal Antibody, 100ul Adenovirus Packaging atherosclerosis and cancer

SKU: 4806860377

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DTBP1 Rabbit Polyclonal Antibody, 100ul Adenovirus Packaging atherosclerosis and cancerThis gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes platelet dense granules and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome related organelles complex 1 (BLOC 1) and binds to alpha and beta dystrobrevins which are components of the dystrophin associated protein complex (DPC). Mutations in this gene are associated with Hermansky Pudlak syndrome

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Description

atherosclerosis and cancer

The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage

which map to chromosomes 12q13 and 21q22

all variants encode the same N-terminus

hematopoietic differentiation

DTBP1 Rabbit Polyclonal Antibody, 100ul Adenovirus Packaging atherosclerosis and cancerThis gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes platelet dense granules and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome related organelles complex 1 (BLOC 1) and binds to alpha and beta dystrobrevins which are components of the dystrophin associated protein complex (DPC). Mutations in this gene are associated with Hermansky Pudlak syndrome

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