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uPA Polyclonal Antibody, 100ul Pipette Filler The major isoform of this

SKU: 46081594094

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uPA Polyclonal Antibody, 100ul Pipette Filler The major isoform of thisPLAU (plasminogen activator, urokinase) encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase type plasminogen activator (HMW uPA). HMW uPA can be further processed into the catalytically active low molecular weight

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Description

The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4

The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters

Upon binding the hormone ligand

This gene is one of two genes that encode the V1 domain C subunit proteins an

and the protein encoded by DAB1 is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain

uPA Polyclonal Antibody, 100ul Pipette Filler The major isoform of thisPLAU (plasminogen activator, urokinase) encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase type plasminogen activator (HMW uPA). HMW uPA can be further processed into the catalytically active low molecular weight

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