Carcinoembryonic Antigen Monoclonal Antibody(10E1), 50ul Centrifugal Filter Mutations in NRL have been

Mutations in NRL have been associated with retinitis pigmentosa and retinal degenerative diseases

The protein encoded by this gene is highly similar to the Saccharomyces cerevisiae SEC15 gene product| which is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast

The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator

This gene is found within an intron of another gene| bladder cancer associated protein| but on the opposite strand

This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain| yielding disulfide-linked heavy and light chains

Carcinoembryonic Antigen Monoclonal Antibody(10E1), 50ul Centrifugal Filter Mutations in NRL have beenThis gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on