DMRT2 Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy CCT8 encodes the theta subunit

CCT8 encodes the theta subunit of the CCT chaperonin

Two pseudogenes of this gene have been identified within this cluster on chromosome 7

epidermal keratinocytes

kb whose expression was highly restricted to circulating NK and T cells

The encoded protein (A-kinase anchoring protein 1) binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion

DMRT2 Rabbit Polyclonal Antibody, 50ul Apoptosis & Autophagy CCT8 encodes the theta subunitThe protein encoded by this gene belongs to the DMRT gene family sharing a DM DNA binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3 genes involved in sex determination in these organisms. Also this gene is located in a region of the human genome (chromosome 9p24. 3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex determining gene(s) on chr 9.