BAM32 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) It is overexpressed in Hodgkin's

It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency

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The coding region is not affected by alternative splicing

and defects in cardiac conduction

BAM32 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) It is overexpressed in Hodgkin'sB cell adapter molecule (BAM32) is also designated dual adapter for phosphotyrosine and 3 phosphotyrosine and 3 phosphoinositide (DAPP1) or B lymphocyte adapter protein. BAM32 is a B cell associated adapter that is crucial for B cell antigen receptor signaling regulation. BAM32 interacts with Ptdlns and PLC g2 and, upon B cell activation, the protein is phosphorylated on tyrosine residues. It is a mainly cytoplasmic protein that can translocate to the