KDM5A Polyclonal Antibody, 50ul High Speed Micro-Centrifuges disease:Defects in AR are the

disease:Defects in AR are the cause of androgen insensitivity syndrome (AIS)

and some types of T-cells

The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates| including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP

The encoded protein has been found in association with intersectin 1 and Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1 when intersectin 1 was isolated from clathrin-coated pits

Among its related pathways areVitamin digestion and absorption and Metabolism of water-soluble vitamins and cofactors

KDM5A Polyclonal Antibody, 50ul High Speed Micro-Centrifuges disease:Defects in AR are theThis gene encodes a member of the Jumonji, AT rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor